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The pharmacological response of participants was assessed at six months
The observed effects were consistent in all investigated subgroups, with a trend toward stronger effects in subjects with T2D and higher cardiovascular risk (77)
Aesthetically over-injection of cheeks can sometimes make temples look hollow even if they are not, but Botox isnt causing the fat or muscle in the temples to prematurely wane
doi: 10.3389/fmed.2026.1810363 Received 13 February 2026 Revised 18 March 2026 Accepted 23 March 2026 Published 04 May 2026 Volume 13 - 2026 Edited by Ramona Cioboata, University of Medicine and Pharmacy of Craiova, Romania Reviewed by Robert Steven Wallis, The Aurum Institute, South Africa Giuseppe Castaldo, University of Naples Federico II, Italy Updates Copyright 2026 Barne, Shevade, Bhattacharyya, Christopher, Nair, Abhyankar, Halder, Vora, Khanna, Swarnakar, Chhajed, Santhalingam, Nair and Salvi
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