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aeruginosa suspended culture and biofilm phenotypes when grown in BSF ( Fig 7 )
PHGDH activation fuels glioblastoma progression and radioresistance via Serine synthesis pathway
In an orthotopic glioblastoma mouse model, PTX-CDs accumulated within intracranial tumours and exerted antitumour effects through ROS-mediated oxidative stress [ At the cellular level, PTX-CDs localised to mitochondria, disrupted mitochondrial membrane potential, and induced oxidative stress-mediated cytotoxicity [ et al
By pairing the synthetic pentadecapeptide with an L-Arginine protective buffer, the compound exhibits an exceptional oral bioavailability profile exceeding 90%
Jacobs RA, Meinild AK, Nordsborg NB, Lundby C
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