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Specifically, the CUB2 and LDLa domains interact with LBDs from GluK2 subunits A/B (or C/D) (Figures 6A,B)
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Acknowledgements We thank A Richter for expert technical assistance, A Klpfer for technical advice and J-M Becht for critical reading of the manuscript
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GLP-1 is produced by l-cells primarily in the distal parts of the intestine, but it can also activate a Gs-coupled GLP-1 receptor (GLP-1R) resulting in proliferation of human coronary artery endothelial cells as well as -cells in pancreas (Egholm et al., 2016)
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