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As in the LEAN study, the primary outcome is histologic resolution of NASH without worsening of fibrosis after 72 weeks of treatment, while secondary outcomes include improvement in liver fibrosis (1 stage) with no worsening of NASH, NAFLD activity score, as well as multiple serum markers of fibrosis
G., Silverman, B
Effective doses appear to start at 100 200 mcg/day.[ref][ref] The RDA for folate from food is 400 mcg/day
Stimuli other than ROS such as excessive ions, high osmolarity, and high temperature were analyzed, but the Cgatg1 strain was not sensitive to these stresses (Supplementary Figure S3)
Sometimes they result in less weight loss results, due to dosing
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