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How to manage fatigue on tirzepatide If you feel tired after taking tirzepatide, several strategies can help combat fatigue while taking this medication
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The clinical trial data from both Phase 2 (Jastreboff et al., NEJM 2023) and Phase 3 (TRIUMPH-4, Eli Lilly press release December 2025) provide a detailed picture of the weight loss trajectory over time
The SURPASS-2 data illustrates this perfectly
If a 10 mg vial would last you longer than 28 days at your current dose, the smaller vial prevents waste from discarding unused medication past its stability window
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