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How its given and how often is very important for treatment
B12: The Basics B12 is a water-soluble vitamin that plays a role in red blood cell formation, metabolism, immune health, DNA synthesis, and brain and nervous system functioning
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The actual injection takes only a few seconds, and any discomfort is typically minimal and brief
Summary: Feeling worse after a B12 injection typically reflects your body adjusting to replenished vitamin levels, triggering metabolic processes that may temporarily cause fatigue, headaches, or injection site discomfort
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![Measuring vitamin B-12 bioavailability with [13C]-cyanocobalamin in humans](https://ars.els-cdn.com/content/image/1-s2.0-S0002916522009297-gr2.jpg)
