1 Engs paper, published in the Journal of Biological Chemistry , noted something strange: exendin-4 shared 53% of its amino acid sequence with a human gut hormone called glucagon-like peptide-1 (GLP-1), which had been characterized just a few years earlier
That sounds bad, until you realize just how rare the cancer is overall
Diabetol Metab Syndr 16 , 307 (2024)
Abstract Background: The purpose of this study was to explore how semaglutide, a GLP-1RA, regulates serum metabolism and gut microbiota to improve obesity in mice and whether fecal microbiota transplantation (FMT) can transmit the beneficial effects of semaglutide to recipient mice
Patients also commonly report improvements in energy, mobility, sleep quality, and confidence