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Cancer-related hypercalcemia and potential treatments
In addition, neuropsychiatric symptoms (e.g., depression, anxiety, sleep disorders) are highly prevalent in AD and are increasingly recognized as a core feature of the disease (124)
Experiments have shown that female mice lacking Ambra-1 displayed autism-like behavior, supporting the findings of inhibited autophagy in ASD [286]
Because GH and IGF-1 promote protein synthesis and lipolysis, these hormonal changes provide a plausible mechanistic basis for modest increases in lean body mass, improved recovery and support for fat loss seen in clinical and observational contexts, but robust controlled trials explicitly measuring those endpoints are still lacking
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