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Phase 2 Obesity Trial New England Journal of Medicine (2023) The pivotal Phase 2 obesity trial of retatrutide, published in the New England Journal of Medicine, enrolled 338 adults with obesity (BMI 30) or overweight with weight-related comorbidities
Dulaglutide BNF/NICE
Example (for a 10mg vial reconstituted in 2 mL of BAC water): Total peptide: 10mg BAC water added: 2 mL Resulting concentration: ~5 mg/mL Recommended practice: Use sterile bacteriostatic water (0.9% benzyl alcohol) for reconstitution
A pregnancy endpoint is not the contemplated route for a sperm-neutral drug
The Bottom Line Lttl's main pricing distinction is dose-based predictability
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