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Because superoxide cannot cross the membrane of mitochondria, it reacts with water to form hydrogen peroxide, which is very susceptible to spontaneously passing out of the membrane [27]
Stegeman I, Eikelboom RH, Smit AL, et al
10.1093/mp/sst080 38 ChenS.JiangH.CaoY.WangY.HuZ.ZhuZ.et al (2016)
For those with autoimmune disorders , stimulating the immune system might not always be advisable
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