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The growing tagged peptides can be precipitated in aqueous solution and other impurities rinsed away before the next cycle starts
If that happens, the accessibility of these drugs could expand rapidly across global populations
Both employ fatty acid acylation of lysine 26 to facilitate serum albumin noncovalent binding to prolong their plasma half-lives (95)
DOI: 10.1159/000358623 [Google Scholar] Wei JP, Yang CL, Leng WH, Ding LL, Zhao GH
The most common side effect is injection site redness, pain, swelling, or irritation
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