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A post hoc analysis of the phase IIb trial showed that tirzepatide was associated with a reduction in the level of high-sensitivity ICAM-1, CRP, and YKL-40 after 26 weeks of treatment in a dose-dependent manner [83, 103]
These included better blood sugar control, blood pressure, and other markers of metabolic health
Around 85% of US adults face weight loss plateaus when their weight loss just pauses or slows down despite maintaining a regimented lifestyle
The case reports suggest that reductions of 15 to 25% from the original levothyroxine dose are common in patients experiencing significant weight loss on GLP-1 agonists
Realistic Expectations Can You Lose 15 Pounds in a Month
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