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Design of a new class of superpotent cyclic -melanotropins based on quenched dynamic simulations
Huveneers S, Phng L-K
It binds to GIP receptors with high affinity (comparable to endogenous GIP), while exhibiting approximately 5-fold lower affinity for GLP-1 receptors compared to native GLP-1
A single 1mL syringe cannot hold enough solution for the full dose
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