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40% reduced -cell mass in DM2 (Maheshvare et al., 2023)

TRAP1, TNF, receptor-associated protein 1

People taking semaglutide for weight loss may experience: Dizziness Fatigue Gastrointestinal issues, such as diarrhea, constipation and gassiness Headache Stomach issues, including nausea, vomiting, pain or distension (bloat) Gastrointestinal issues are the most common complaint among people just starting semaglutide