Now, Lilly recently reported topline results from the ATTAIN-1 phase-3 trial evaluating orforglipron, a once-daily oral glucagon-like-peptide-1 (GLP-1) receptor agonist for adults with obesity or overweight without diabetes
Neurological, psychiatric, and biochemical aspects of thiamine deficiency in children and adults
It stimulates ACTH and cortisol release (likely through hypothalamic CRH activation), increases prolactin secretion, and potently stimulates appetite through ghrelin-mimetic activity at the GHS-R1a receptor in the arcuate nucleus
"To control blood glucose spikes, combine protein with carbohydrates, like rice with beans, or cottage cheese or yogurt with fruit," says Nasser
Mumbauer S, Pascual J, Kolotuev I, Hamaratoglu F