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As a result, there has been interest in the use of insulin-sparing agents: glucagon-like peptide-1 receptor agonists (GLP-1 RA) in HNF1A-MODY,1012 GLP-1 RA in HNF4A-MODY,13 and dual glucose insulinotropic polypeptide (GIP)/GLP-1 RA in HNF1A-MODY and HNF4A-MODY.14 Despite the previous case reports, there has been a lack of statistical comparisons in larger cohorts of MODY describing the glycemic and weight-lowering effect of GLP-1 RA and dual GIP/GLP-1 RA
Some studies suggest comparable efficacy to 5% Minoxidil
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