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Early trial results for oral VK2735 show promising weight-loss results with manageable side effects
Practitioners should note that they only work when combined with a healthy lifestyle that promotes weight loss
A man who begins enclomiphene but continues to gain weight and sleep poorly may find that his response attenuates over time
The handoff is internal
Importantly, initiation of GLP-1RA may decrease levothyroxine dose requirements in patients with hypothyroidism through weight loss, enhance levothyroxine absorption due to delayed gastrointestinal (GI) transit, and have direct effects on the hypothalamic-pituitary-thyroid axis [23,24,25,26,27,28,29], potentially increasing the risk of thyroid hormone over-replacement (i.e., iatrogenic hyperthyroidism)
