Furthermore, recent studies show the benefits of tirzepatide in people with metabolic dysfunctionassociated steatohepatitis (MASH) [5], in people with heart failure with preserved ejection fraction (HFpEF) and obesity [6], and in people with T2D with established atherosclerotic cardiovascular disease according to a recent press release [7]
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8 SUMMIT also demonstrated significant improvements in patient-reported outcomes: at 52 weeks, tirzepatide increased KCCQ-CSS, with a between-group mean difference of 6.9 points, and increased 6-minute walk distance, with a between-group mean difference of 18.3 m
Eating Disorders The appetite-suppressing effects of GLP-1 drugs can lead to disordered eating patterns, including: Anorexia : A significant reduction in food intake that can result in malnutrition
Lancet 396 , 12231249 (2020)