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When autophagy is inhibited, SFN retains the ability to activate Nrf2 and its downstream targets, yet the membrane translocation of SLC7A11 and its cystine transport function are substantially diminished, ultimately attenuating SFN's anti-ferroptosis effect

Otherwise, intra-abdominal hypertension adversely affects many organs, such as the brain, heart, lungs, kidneys, and gastrointestinal tract ( Furthermore, as an immediate effect, the abdominal, thoracic, and cranial cavities interact with each other (Youssef et al., 2012

Role of STAT3 signaling pathway in breast cancer

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