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FIGURE 1 2.2 Search strategy A systematic search of scientific literature was conducted in the Web of Science (Core Collection), Scopus, and PubMed databases, including studies published up to November 2025 without country restrictions
Food and Drug Administration, Global Substance Registration System
Caffeine can help and hurt SCD patients, so finding the right amount is key
The primary difference lies in their mechanisms of action
they are the direct results of measurable, biochemical dysfunctions at the cellular level
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