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10.1177/1010428317717655 67 JansovH.imnekT
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In each group, 30,000 cells were initially analysed using FACS and 21,00024,000 cells were eventually included in statistical analysis
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In colonic tissue models, gabapentin was associated with: Reduced mast cell density or activation markers Decreased release of inflammatory mediators Improvement in visceral pain signaling These findings suggest gabapentin may exert indirect mast cellregulating effects within colonic tissue in experimental models
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