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Glutathione (GSH) is the endogenous tripeptide gamma-L-glutamyl-L-cysteinyl-glycine, molecular formula CHNOS, molecular weight 307.32 g/mol, CAS 70-18-8
J Diabetes Res 2019:8905917 Yu W, Zha W, Ren J (2018) Exendin-4 and liraglutide attenuate glucose toxicity-induced cardiac injury through mTOR/ULK1-dependent autophagy
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Most of phase 2 reactions take place in cytosol and involve conjugation with endogenous compounds via transferase enzymes
En el estudio AWARD-11 se evalu el tratamiento con dosis de 1,50, 3 y 4,50mg de dulaglutida presentando una perdida ponderal promedio de 2,40, 3 y 4kg, respectivamente (2,40, 3,20 y 4%)26
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