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10 Pharmacists who are aware of cases of exenatide-associated acute pancreatitis or other serious adverse drug reactions are encouraged to report their findings to MedWatch, the FDAs adverse drug reporting program (www.fda.gov/Safety/MedWatch/ Anti-exenatide Antibodies: In phase III clinical trials, 41% to 49% of patients receiving exenatide developed anti-exenatide antibodies

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Moreover the IGF1 axis, which can be stimulated by excessive levels of circulating insulin, is one of the key pathways involved in proliferative responses in both normal and neoplastic thyroid cells (Vella et al., 2001

While diabetes and obesity remain the primary targets, emerging research into new indications offers a transformational opportunity for market growth