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In animal models finerenone reduced the expression of genes encoding monocyte chemoattractant protein-1, matrix metalloproteinase-2 and plasminogen activator inhibitor-1 (related to tissue remodelling and fibrosis) in the kidney, and additionally demonstrated beneficial immunomodulatory effects [73]
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Dosage must be measured precisely using an appropriate low-volume syringe and determined by a licensed healthcare provider
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