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Slower gastric emptying means you feel fuller longer, which reduces appetite and promotes weight loss

Then, Parkin ubiquitinates outer mitochondrial membrane proteins to trigger selective autophagy [75, 82, 83]

STEP 2 studied participants with both obesity and type 2 diabetes

"Losing weight has a tendency to improve body image, self-esteem, and even mobilitythese are all things that help with mental health," Thea Gallagher, PsyD, clinical associate professor of psychology at NYU Langone Health, tells SELF

A typical taper from 12mg might step down to 8mg for two weeks, then 4mg for two weeks, then 2mg for two weeks before stopping entirely