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Some people may be more sensitive to medications, which could increase their chances of having side effects like leg cramps
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The SUSTAIN-7 trial (40 weeks comparing semaglutide 0.5 mg and 1 mg to dulaglutide) reported no confirmed pancreatitis cases in either semaglutide arm during the maintenance phase, though the trial was not powered for this endpoint
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Patients carrying specific alleles of this variant may experience more pronounced A1C drops or require different dosing strategies for optimal results
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