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In the pancreas, GLP-1 stimulates insulin secretion from -cells in a blood-glucose dependent manner, while inhibits glucagon secretion from -cells, thus playing an essential role in blood glucose regulation 15, 16 .The physiological properties of GLP-1 have rendered it an attractive target for diabetes treatment
When taken for a long term, it is associated with a decrease in zinc level and also causes toxicity to the liver
FDA status: Semaglutide is FDA-approved
This makes protein optimization and resistance training even more critical for older researchers, who should aim for the higher end of protein recommendations (1.2 to 1.6 grams per kilogram daily) and prioritize strength training over cardiovascular exercise
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