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Semaglutide is FDA-approved for adolescents 12 and older for obesity, and tirzepatide is approved for adolescents 10 and older for Type 2 diabetes

The pathological status and healing process of wounds were evaluated by H&E staining and Massons trichrome staining

injection with 100 nmol kg 1 MK-801 ( n = 7 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice) or vehicle (isotonic saline, n = 8 mice) in lean mice