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In 2021, Kishimoto et al., in a double-blind, placebo-controlled clinical trial, evaluated the anti-inflammatory effects of curcuRouge for 4 weeks on systemic inflammation in adults over 60 years of age in Japan [62]

What we DO know, however, is that only 20% (or even less) of the people with symptomatic B12 deficiency have anaemia or altered size of the red blood cells

No downtime is required, and any mild discomfort is temporary

Markers of apoptosis, including elevated Bax and caspase-3 along with reduced Bcl-2, were significantly dysregulated in the STZ-induced diabetic group in this study, indicating enhanced pro-apoptotic signaling and mitochondrial dysfunction 55,56