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Description

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Amber vials or secondary containers provide additional protection

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The REDEFINE 3 cardiovascular outcomes trial which will take several years to complete is not a prerequisite for initial market authorisation for obesity treatment, but its results will likely be important for subsequent label expansion and for establishing the cardiovascular benefit profile that has proven so valuable for tirzepatide and semaglutide

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Normally only about 10% of total transcobalamin is bound to B12, whereas in contrast haptocorrin carries about 80% of the B12 in the circulation, despite having no role in the cellular uptake of vitamin B12 (Sobczynska-Malefora & Smith, 2022)

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