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Patients should also report diarrhea that significantly impacts quality of life or prevents maintaining adequate nutrition and hydration

When these symptoms show up, higher doses of vitamin B12 may be needed to help

During the proliferation phase, neovascularization is essential for delivering nutrients and oxygen to the wound site, thereby promoting fibroblast proliferation, collagen synthesis, and re-epithelialization 73

Because the pill is taken daily and requires higher doses to be absorbed, some patients find it harder to tolerate or harder to take consistently

There is no universal sleep-friendly injection, but side effects usually lessen over time