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[10] The first amylin analogue to reach the clinic, pramlintide, demonstrated that the pathway could be drugged, but native-style amylin analogues are short-acting and were used as multiple-daily injections, which limited their appeal for weight management
In case there are persistent side effects such as skin rashes, allergies or other worrying signs, medical advice should be sought urgently
doi:10.1016/j.phrs.2006.04.003 13
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