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injection with 100 nmol kg 1 MK-801 ( n = 7 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice) or vehicle (isotonic saline, n = 8 mice) in lean mice
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Wang Y, Zhang J, Ren S, Sun D, Huang HY, Wang H, et al
Within the vascular system, oxidized low-density lipoprotein enhances superoxide generation through multiple pathways, including the induction of uncoupled endothelial NOS, activation of NADPH oxidase and xanthine oxidase enzymes, and disruption of mitochondrial electron transport chain function [139]
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