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Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as add-on to metformin in patients with type 2 diabetes in sustain China: A 30-week, double-blind, phase 3a, randomized trial
More anxiety, insomnia, headaches, and more sensitivity to foods high in histamine
Allergic reactions are possible, though infrequent
The team made three simultaneous changes to the GLP-1 backbone: a position-8 amino acid substitution to block DPP-4 cleavage, an arginine substitution to prevent fatty-chain attachment at the wrong lysine, and attachment of a C18 fatty diacid chain via a short PEG linker at lysine-26
Foods 6(7):47 Nomi Y, Iwasaki-Kurashige K, Matsumoto H (2019) Therapeutic effects of anthocyanins for vision and eye health
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