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On-Label vs Off-Label and Compounded Products Vitamin B12 injections are an established medical treatment for confirmed B12 deficiency and related conditions (for example, pernicious anemia and certain malabsorption states), as summarized by the NIH Office of Dietary Supplements in its Vitamin B12 fact sheet for health professionals
This is partially true: BPC-157 contains multiple proline residues, and proline-containing peptides have known resistance to some proteases
Those with severe deficiencies may require higher doses of vitamin B12, which can cause side effects including dizziness, headache, anxiety, nausea, and vomiting (Al Amin, 2021)
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