Several other investigators have also revealed that the activation of IGF-1R stimulated the p53-dependent cellular senescence, e.g., in human and mouse fibroblasts, human mesangial cells, and rat vascular smooth muscle cells [144,145,146]
doi: 10.1038/s41586-023-06255-6 47 LiWLiangLLiuSYiHZhouY
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