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Both are GLP-1 receptor agonists, but tirzepatide also activates GIP receptors making it a dual agonist
doi: 10.1080/01635581.2021.2007962 137
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Animals were not used for multiple experiments as two of the three experiments were non-survival (due to the blood collection following DMRS and the urethane anesthesia used for fMRI) and incompatible (DMRS and PET both required labeled glucose injection, the DMRS and fMRI signals may interfere with each other, and fMRI required different anesthesia than the other two experiments)
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Asct2 (Slc1a5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma
