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Presented for research literature review only Satheesh P et al
These beneficial effects were attributed to a reduction in ROS synthesis, and when ROS levels were decreased, the observed improvements were reversed (Ahmadi and Khalatbary 2021)
Although energy metabolism status can also regulate intracellular ROS levels (e.g., glucose deprivation leads to a marked increase in cellular ROS) [53,54,55,56], our study demonstrated that supplementation with energy substrates such as sodium pyruvate in GGCT-knockdown cell models did not induce significant alterations in intracellular ROS levels
The rising popularity of glutathione has yet to clarify its original function
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