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This reduction in ROS is relevant because ROS-dependent signaling pathways regulate mitochondrial redox balance and tricarboxylic acid cycle-associated gluconeogenesis [9]
Cisplastin may increase urinary excretion of carnitine
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These injuries range from painful gastrointestinal conditions like stomach paralysis and delayed gastric emptying to more alarming complications such as vision loss, deep vein thrombosis (DVT), and other serious health risks
It's important to note that weight loss itself is an evidence-based therapy for GERD, so the weight reduction achieved with these medications may actually improve reflux symptoms in some patients, potentially offsetting any direct effects on the gastroesophageal junction
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