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Oral preparations of Vitamin B12 may increase serum levels but many patients remain symptomatic until they use sublingual or vitamin B12 injections due to low cellular concentrations 6

Epub 2022/12/12

It acts by inhibiting mitochondrial complex I, which reduces ATP production, which results in compensatory upregulation of glycolysis, secondary lactate production, and oxidative stress [434]

2.4.1 Inflammation Oxidative stress is a potent trigger and amplifier of the inflammatory response in the ischemic and reperfused myocardium