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Use of popular weight-loss drugs was associated with improved survival and reduced risk of recurrence for women with breast cancer and obesity or type 2 diabetes, according to study results published in JAMA Network Open
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Anti-inflammatory NF-B Modulation MC1R and MC3R activation by melanocortin peptides has been shown to suppress NF-B nuclear translocation and downregulate pro-inflammatory cytokine production (TNF-, IL-6, IL-1) in macrophage and keratinocyte models, suggesting a role in cutaneous inflammatory signaling research (Luger et al., Journal of Investigative Dermatology, 1997)
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