The foundation of research backing GHK-Cus efficacy is strong, its mechanisms of action are sound, and the safety profile works in the peptides favor
In cosmetic product studies, GHK-Cu was found to tighten loose skin, improve elasticity, density, and firmness, and reduce fine lines, wrinkles, photodamage, and hyperpigmentation
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Then, in 2015, Lee and colleagues identified a previously overlooked open reading frame within the 12S ribosomal RNA gene of mtDNA and found that it encodes a functional peptide, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) [1]