Called GLP-1 RAs or GLP-1 meds for short, glucagon-like peptide-1 receptor agonists are a class of drugs used to treat type 2 diabetes and obesity
The agency said it intends to take steps to restrict GLP-1 active pharmaceutical ingredients (APIs) intended for use in non-FDA-approved compounded drugs that are being mass-marketed by companies, including Hims & Hers and other compounding pharmacies, as similar alternatives to FDA-approved drugs. This led Hims & Hers to halt sales of certain, lower-cost, non-FDA-approved, copycat versions of drugs like Wegovy and Ozempic
There is no absolute contraindication to using GLP-1 receptor agonists in patients with hypothyroidism, and these medications work through different pathways than thyroid hormone replacement therapy (levothyroxine)
While Ozempic is indicated for type 2 diabetes, research on semaglutide has shown that it can lead to significant weight loss
He added that even those with lower adherence saw some of these benefits