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291 Additionally, VSMC transdifferentiation and apoptosis are common pathogenic mechanisms in aortic aneurysm/dissection and are associated with lactylation

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Bulk RNA sequencing revealed that gene expression changes were most pronounced in the MBH, where RAMP1/3 KO mice treated with sCT showed extensive differential expression of over 1,700 genes, while WT mice exhibited comparatively minor transcriptional shifts

[6] Semax affects expression of immune- and vascular-system genes in the brain (2014), PubMed

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