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Additionally, genetic factors affecting the FTO gene and metabolic regulation can influence antioxidant demands
No adverse events associated with LC administration were recorded at a dose 6 g/day for 12 months of supplementation in the patients with acute anterior myocardial infarction [87], or at a dose 1.274 g/day (range 0.33 g/day) and duration 348 days (range 93744 days) in patients with liver cirrhosis [88]
Excessive H 2 O 2 reacts with Fe 2+ via Fenton chemistry, yielding highly toxic hydroxyl radicals, culminating in lipid peroxidation and apoptosis of nigral neurons
This mechanism relies on intact pituitary and hypothalamic function, making efficacy dependent on baseline hormonal reserve and individual receptor sensitivity
| Int J Cardiol
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