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In summary, EGCG-induced hepatotoxicity involves the inhibition of major antioxidant enzymes, with the Nrf2 salvage pathway playing a crucial role in mitigating toxicity
Low glutathione levels are associated with a weakened immune response
However, brain glutathione levels may be relatively stable or regionally affected
FMT in capsule form has also demonstrated safety and the potential to enhance ICB responsiveness in gastrointestinal cancers (NCT04130763)
More serious concerns include allergic reactions, which can manifest as redness, swelling, or persistent irritation
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