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The primary theoretical safety concern is sustained activation of the HGF/c-Met proto-oncogenic pathway, which could theoretically promote tumor initiation or growth
Its documented effects are primarily related to cellular repair, inflammation control, and vascular health
PPH00333B for c-FLIP
Once MSCs reach the damaged site, they secrete a variety of bioactive molecules, including growth factors, anti-inflammatory mediators, and antioxidants, thereby creating a therapeutic microenvironment (Gnecchi et al., 2016)
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