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The mechanism is linked to the regulation of gut microbiota and inhibition of LPS and TMAO-induced PI3K/AKT/NF-B signaling pathways
Choline is required by cells to make two key second messenger molecules in particular: DAG (diacylglycerol) ceramide These second messenger molecules are used in cell signalling pathways that regulate a variety of cell responses, including smooth muscle contraction, secretion by glands, and programmed cell death (apoptosis) in response to damage
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Dietary choline is inversely associated with depressive symptoms: A cross-sectional study of the National Health and Nutrition Examination Survey (NHANES) 2011 to 2018
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