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In general, only 5% of primary BAs is not reabsorbed in the gut and undergo biotransformation to secondary Bas [25]
Macrophage-derived AIM Is endocytosed into adipocytes and decreases lipid droplets via inhibition of fatty acid synthase activity
Both GABA and serotonin availability declined with reduced receptor expression for GABA A 2 and GABAB1 in prefrontal cortex in the 2 week CMS (Tyagi et al., 2025)
Considerable evidence indicates that insulin signaling abnormalities, both peripherally and centrally, are associated with AD and cognitive decline [137]
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