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53 Finally, tirzepatide is a GLP1R/GIPR dual agonist, currently being evaluated in phase 3 trials

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Sudden vision loss in one or both eyes, even if painless A curtain or shadow blocking part of your visual field A sudden burst of many new floaters or flashing lights Severe eye pain accompanied by decreased vision or nausea Any vision change that significantly affects your daily activities or safety How We Diagnose Semaglutide-Related Eye Changes We begin by placing drops in your eyes to enlarge your pupils, allowing us to see the entire retina and optic nerve

For larger time zone shifts (traveling to Europe or Asia), the same principle applies with more flexibility